Reproductive Potential Impacts Body Maintenance Parameters and Global DNA Methylation in Honeybee Workers (Apis mellifera L.)

The widely accepted hypothesis in life history evolution about the trade-off between fecundity and longevity is not confirmed by long-living and highly fecund queens in eusocial insects.The fact that the queens and facultatively sterile workers usually arise from genetically identical eggs but differ in DNA methylation makes them a good model for s

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The Impact of Innate Components on Viral Pathogenesis in the Neurotropic Coronavirus Encephalomyelitis Mouse Model

Recognition of viruses invading the central nervous system (CNS) by pattern recognition receptors (PRRs) is crucial to elicit early innate responses that stem dissemination.These innate responses Inlet Filter comprise both type I interferon (IFN-I)-mediated defenses as well as signals recruiting leukocytes to control the infection.Focusing on insig

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Greedy permanent magnet optimization

A number of scientific fields rely on placing permanent magnets in order to produce a desired magnetic field.We have shown in recent work that the placement process can be formulated as sparse regression.However, binary, grid-aligned solutions are desired for realistic engineering designs.We now show that the binary permanent magnet problem can be

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